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In some embodiments, the otic formulation or composition comprises about 20% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

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5 Mitochondrial GSH depletion sensitizes cells to BSO treatment

123,181,182,183,184 Consequently, diminishing APOE4 expression in A plaque-associated microglia may offer an effective approach

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Its stability and bioavailability make it one of the most studied tissue-repair peptides in preclinical research